Reflex Sympathetic Dystrophy
April 2018 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Reflex Sympathetic Dystrophy abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Reflex Sympathetic Dystrophy. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Reflex Sympathetic Dystrophy. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Reflex Sympathetic Dystrophy every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content, Inc.

1:Low-Dose Intravenous Immunoglobulin Treatment for Long-Standing Complex Regional Pain Syndrome: A Randomized Trial.
Authors:Goebel A, Bisla J, Carganillo R, Frank B, Gupta R, Kelly J, McCabe C, Murphy C, Padfield N, Phillips C, Sanders M, Serpell M, Shenker N, Shoukrey K, Wyatt L, Ambler G
Institution:From University of Liverpool and The Walton Centre National Health Service (NHS) Foundation Trust, Liverpool; Institute of Psychiatry, Psychology and Neuroscience, Guy's and St Thomas' Hospital, and University College London, London; Modepharma Limited, Beckenham; Queen Elizabeth University Hospital, Glasgow; University West of England, Bristol; Swansea University, Swansea; Norfolk and Norwich University NHS Trust, Norwich; Cambridge University Hospitals, Cambridge; and University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
Journal:Ann Intern Med. 2017 Oct 3;167(7):476-483. doi: 10.7326/M17-0509. Epub 2017 Sep 12.

2:Complex Regional Pain Syndrome Diagnosed with Triple-Phase Bone Scanning.
Authors:Kaur H, Muhleman M, Balon HR
Institution:Department of Diagnostic Radiology and Molecular Imaging, Beaumont Hospital, Royal Oak, Michigan Royal Oak, Michigan. Royal Oak, Michigan.
Journal:J Nucl Med Technol. 2017 Sep;45(3):243-244. doi: 10.2967/jnmt.117.192443. Epub 2017 Jun 13.

3:Case Study of High-Dose Ketamine for Treatment of Complex Regional Pain Syndrome in the Pediatric Intensive Care Unit.
Authors:Pasek TA, Crowley K, Campese C, Lauer R, Yang C
Institution:Pain, Pediatric Intensive Care Unit, Evidence-Based Practice and Research, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. Electronic address: Pittsburgh Medical Center, Pittsburgh, PA, USA. Pittsburgh Medical Center, Pittsburgh, PA, USA. Pittsburgh Medical Center, Pittsburgh, PA, USA. Pittsburgh Medical Center, Pittsburgh, PA, USA.
Journal:Crit Care Nurs Clin North Am. 2017 Jun;29(2):177-186. doi: 10.1016/j.cnc.2017.01.005. Epub 2017 Mar 13.

4:Remote ischaemic conditioning decreases blood flow and improves oxygen extraction in patients with early complex regional pain syndrome.
Authors:Hegelmaier T, Kumowski N, Mainka T, Vollert J, Goertz O, Lehnhardt M, Zahn PK, Maier C, Kolbenschlag J
Institution:Department of Pain Medicine, BG University Hospital Bergmannsheil, Ruhr University, Bochum, Germany.; Department of Neurology, University Medical Center Hamburg Eppendorf, Germany.; Center of Biomedicine and Medical Technology Mannheim (CBTM), Medical Faculty Mannheim, Heidelberg University, Germany.; Department of Plastic and Hand Surgery, Burn Center, BG University Hospital Bergmannsheil, Ruhr University, Bochum, Germany.; Department of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Martin-Luther-Hospital, Berlin, Germany.
Journal:Eur J Pain. 2017 Sep;21(8):1346-1354. doi: 10.1002/ejp.1033. Epub 2017 Mar 24.

5:Novel Signs and Their Clinical Utility in Diagnosing Complex Regional Pain Syndrome (CRPS): A Prospective Observational Cohort Study.
Authors:Kuttikat A, Shaikh M, Oomatia A, Parker R, Shenker N
Institution:*Department of Rheumatology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust daggerSchool of Clinical Medicine double daggerCentre for Applied Medical Statistics, University of Cambridge, Cambridge, UK.
Journal:Clin J Pain. 2017 Jun;33(6):496-502. doi: 10.1097/AJP.0000000000000434.

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What Our Customers Are Saying...

"Your MediFocus Guidebook on Reflex Sympathetic Dystrophy helped me understand my diagnosis. It gave me a clear insight into what the disorder is about and a way to find out about the treatments for RSD. It also gave me a way to inform those around me. Anyone who has RSD or knows someone who is diagnosed with RSD needs this easy to read and understand Guidebook."
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